Expert Report on Multiple Imputation
نویسنده
چکیده
This report provides a review of the multiple imputation methodology used by the Sponsor (Acorn Cardiovascular, Inc.) to handle missing data in the analysis of the primary endpoint of its pivotal clinical trial of the CorCap Cardiac Support Device (CorCap), as well as an evaluation of the impact of multiple imputation on the results of that analysis. This included a completely blinded imputation briefly described at the end.
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